BIOS 255 Week 5 Immune System

Name

Chamberlain University

BIOS-255: Anatomy & Physiology III with Lab

Prof. Name

Date

Immune System

Learning Objectives:

Discuss the fundamental need for the immune system.
Identify physical and chemical barriers against pathogenic invasion.
Describe mechanisms of immune invasion by pathogens.
Predict the outcome of scenarios of immune deficiency.
Summarize the key features of innate and adaptive immune responses.
Describe antigen-antibody interactions.
Classify immune cell types by their role in responses.
Define immunological memory and its importance.

Introduction:

Immunity refers to the body’s ability to defend itself against disease and infection. Immunity can be categorized into two different forms: innate or adaptive. We will explore these two types of immunity in detail. Have you ever wondered what infections look like from the pathogen’s perspective? If our immune systems are so effective, why do we still get sick? The immune system is a complex network of cells and tissues that work together to protect the body from infection.

In this simulation, you will take on the role of a pathogen attempting to establish an infection in a human body. You will encounter the major cells and organs of the immune system as they work to eliminate you. Through this interactive experience, you will gain a better understanding of how immune cells destroy invading pathogens. By examining historical data maps, you will also learn how an individual’s immunological status influences both personal health and the spread of disease in their community. Additionally, you will meet the key cells involved in immune memory and explore the role of immunization in preventing diseases. This simulation will prepare you for a global health investigation challenge.

Assignment:

Part 1

Labster “Introduction to Immunology: Explore the Immune System and Save the World.” As you complete the lab, be sure to have your lab report ready to record data. The theory section of the lab will be a helpful resource.

Part 2

Complete the lab report.

Immune System Lab Report

Describe components of the immune system by completing the following chart:

Description/Function
Innate immunity	Adaptive immunity	IgG	IgM	IgA	IgE	Thymus
First line of defense; does not have memory components, and does not change when it encounters an infected cell. Involves macrophages and NK cells.	Appears when someone has received a vaccine or has been exposed to a virus; involved in adaptive immune response.	Produced when fighting off an active infection.	Appears during an active infection.	Found in mucosal areas such as the gut and respiratory tract, provides protection against pathogens.	Involved in allergic reactions when the body encounters allergens.	Where T-cells mature.

What is the primary mode by which a macrophage engulfs pathogens?
Phagocytosis.
What is a major functional difference between B cells and T cells?
B cells are involved in antibody-mediated immunity, while T cells are involved in cell-mediated immunity.
Identify two methods of immune evasion by pathogens:
Pathogens evade the immune system through antigenic variation and latency.
Record the data from the samples:

Antibody Detected	Sample 1	Sample 3	Sample 7	Sample 8
IgM	+	–	+	–
IgG	–	+	–	+

Interpret the results of Samples 1, 3, 7, and 8:

Evidence of Current Exposure/Infection?	Sample 1	Sample 3	Sample 7	Sample 8
Yes	No	Yes	Yes	No

Evidence of Previous Exposure Only with No Current Infection?	Sample 1	Sample 3	Sample 7	Sample 8
No	Yes	No	No	Yes

Discuss the benefit of vaccinations:
Vaccines are beneficial because they provide a weakened form of the virus, which stimulates an adaptive immune response. This allows the immune system to remember how to fight the virus when it encounters it naturally, resulting in a quicker and more effective immune response that can kill the virus before it causes significant harm.

BIOS 255 Week 5 Immune System

Grading Rubric for Lab Report Activity

Deliverable	Points
Part 1: Complete Labster	15
Part 2: Complete lab report	15
Total	30