NR 716 Week 4 Translation Science and Synthesis

NR 716 Week 4 Translation Science and Synthesis

NR 716 Week 4 Translation Science and Synthesis

Name

Chamberlain University

NR-716: Analytic Methods

Prof. Name

Date

Evidence Synthesis: Heart Failure

Heart failure (HF) is a progressive and multifaceted chronic condition characterized by the heart’s inability to pump adequate blood to meet the metabolic needs of the body. This insufficient cardiac output makes long-term management difficult (Piña et al., 2021; Centers for Disease Control and Prevention [CDC], 2019). Congestive heart failure (CHF) is commonly linked to modifiable lifestyle risk factors such as smoking, high sodium and cholesterol diets, excessive alcohol consumption, and sedentary behavior (CDC, 2023; Ding et al., 2020; Mohammadi et al., 2021; Pereira Sousa et al., 2021). Additionally, comorbidities such as hypertension, diabetes, obesity, and coronary artery disease significantly elevate the risk of developing HF (CDC, 2023).

Preventive strategies play a pivotal role in reducing morbidity and mortality. Early diagnosis of cardiovascular complications allows timely initiation of treatment (World Health Organization [WHO], 2021). Furthermore, strong social and clinical support networks are essential for lowering patient stress, encouraging adherence to prescribed regimens, and improving overall quality of life (Singh et al., 2021). This evidence synthesis evaluates national and state-level HF outcomes, reviews both research and non-research evidence, and emphasizes the role of multimedia education, teach-back strategies, and reflective learning in minimizing anxiety, reducing hospital readmissions, and strengthening self-management.

Analysis

CHF is one of the leading causes of morbidity and mortality globally. Effective management requires patient competency in symptom recognition, medication compliance, lifestyle adjustments (dietary restrictions, physical activity), and daily monitoring practices such as weight checks (Mohammadi et al., 2021; Ding et al., 2020). Although the heart continues to function, reduced circulation limits oxygen supply to vital organs, predisposing patients to frequent hospitalizations when self-care is inadequate.

Patient education is critical to HF care, as it equips individuals to manage their condition and reduces readmissions (Pereira Sousa et al., 2021). Epidemiological reports estimate that 6.7 million U.S. adults aged 20 and older live with HF, a figure projected to increase to 8.5 million by 2030 (CDC, 2023). Globally, incidence ranges from 1–9 per 1,000 persons annually, with higher prevalence in adults over 55 years (Groenewegen et al., 2020).

Racial and Geographic Disparities

Disparities in mortality rates highlight inequities in cardiovascular health. In 2020, African Americans had the highest HF mortality at 675.4 per 100,000 compared to Hispanics at 154.8 per 100,000 (CDC, 2020). National data also revealed African Americans experienced nearly double the mortality rate of Hispanics (Mujib et al., 2011). Geographically, southeastern states, including Alabama and Mississippi, demonstrated the highest burden of HF-related mortality (CDC, 2020).

Economic Burden

HF imposes substantial financial strain. The average annual healthcare expenditure per patient in the United States is approximately $30,000 (Heidenreich et al., 2022). These costs are exacerbated by recurrent hospital readmissions. Sustainable strategies, such as continuous education, follow-up monitoring, and structured care coordination, are vital to alleviating both health and financial burdens.

Evidence Synthesis

Review of three randomized controlled trials (RCTs) revealed consistent challenges in HF care, including poor self-management and limited provider support. Interventions such as telemonitoring, patient-centered education, symptom recognition training, and teach-back methods showed notable benefits (Ding et al., 2020; Mohammadi et al., 2021; Pereira Sousa et al., 2021). Patients exposed to reflective learning approaches demonstrated better disease comprehension, improved treatment adherence, and reduced readmission rates.

Comparative Summary of the Three Studies

StudyDesignKey InterventionFollow-Up PeriodKey Findings
Mohammadi et al. (2021)RCTMultimedia education + teach-back8 weeksImproved quality of life, reduced cardiac anxiety, decreased hospital readmissions
Pereira Sousa et al. (2021)RCTSymptom recognition + self-care training10 weeksEnhanced patient adherence and awareness of self-care practices
Ding et al. (2020)RCTTelemonitoring + comprehensive care program12 weeksHigher compliance rates, fewer hospitalizations

Across all studies, consistent evidence supports the effectiveness of technology-driven education, continuous provider engagement, and patient reflection strategies.

Practice Question

In patients aged 18–60 with heart failure (P), how does multimedia education with teach-back and reflective learning (I), compared to multimedia education only (C), reduce patient anxiety, hospital readmission, and improve quality of life (O) within 8–10 weeks (T)?

Evidence supports that structured education, particularly when reinforced with follow-up, significantly decreases readmission rates (Rahmani et al., 2020). Combining teach-back with reflective learning ensures patients thoroughly understand clinical guidance, enhancing long-term self-management and improving overall well-being.

Translation Science Theory

The Knowledge-to-Action (KTA) framework provides a systematic approach to translating evidence into practice (Lee & Ho, 2019).

Components of KTA Application in HF Care

  1. Knowledge Creation – Identifying gaps in HF management, particularly inadequate patient education.

  2. Adaptation – Incorporating multimedia resources and reflective learning into discharge planning.

  3. Barrier Assessment – Addressing low health literacy, socioeconomic barriers, and lack of support systems.

  4. Implementation – Delivering structured education reinforced by teach-back and follow-up visits.

  5. Monitoring and Sustainability – Tracking readmission rates, patient-reported outcomes, and adherence trends.

Interprofessional collaboration—nurses, physicians, dieticians, case managers, and patients—is essential for effective long-term outcomes (Quanbeck, 2019; Ten Ham-Baloyi, 2022). This collaborative approach fosters patient-centered care and supports sustainability.

Conclusion

Heart failure continues to be one of the most prevalent, costly, and life-threatening chronic diseases worldwide. A major contributor to poor outcomes is patients’ limited knowledge and self-care capacity. Evidence indicates that incorporating multimedia education, teach-back, and reflective learning strengthens patient understanding, reduces anxiety, and lowers readmissions.

References

Centers for Disease Control and Prevention. (2019). Hospitalization for congestive heart failure, United States. https://www.cdc.gov/nchs/products/databriefs/db108.htm

Centers for Disease Control and Prevention. (2020). Interactive atlas of heart disease and stroke. https://nccd.cdc.gov/DHDSPAtlas/reports.aspx

Centers for Disease Control and Prevention. (2022). Public health action plan to prevent heart disease and stroke. https://www.cdc.gov/dhdsp/action_plan/pdfs/action_plan_full.pdf

Centers for Disease Control and Prevention. (2023). Facts of heart failure in the United States. https://www.cdc.gov/heartdisease/heart_failure.htm

Ding, H., Jayasena, R., Chen, S., Maiorana, A., Dowling, A., Layland, J., Good, N., Karunanithi, M., & Edwards, I. (2020). The effects of telemonitoring on patient compliance with self-management recommendations and outcomes of the innovative telemonitoring enhanced care program for chronic heart failure: Randomized controlled trial. Journal of Medical Internet Research, 22(7), e17559. https://doi.org/10.2196/17559

Groenewegen, A., Rutten, F., Mosterd, A., & Hoes, A. (2020). Epidemiology of heart failure. European Journal of Heart Failure, 22(8), 1342–1356. https://doi.org/10.1002/ejhf.1858

Heidenreich, P. A., Fonarow, G. C., Opsha, Y., Sandhu, A. T., Sweitzer, N. K., Warraich, H. J., & HFSA Scientific Statement Committee Members. (2022). Economic issues in heart failure in the United States. Journal of Cardiac Failure, 28(3), 453–466. https://doi.org/10.1016/j.cardfail.2021.12.017

Lee, C., & Ho, K. (2019). Knowledge to action framework for home health monitoring. Healthcare Management Forum, 32(4), 183–187. https://doi.org/10.1177/0840470419855364

Mohammadi, F., Jahromi, M. S., & Bijani, M. (2021). Investigating the effect of multimedia education in combination with teach-back method on quality of life and cardiac anxiety in patients with heart failure: A randomized clinical trial. BMC Cardiovascular Disorders, 21(1), 535. https://doi.org/10.1186/s12872-021-02357-z

Mujib, M., Zhang, Y., Feller, M. A., & Ahmed, A. (2011). Evidence of a “heart failure belt” in the southeastern United States. The American Journal of Cardiology, 107(6), 935–937. https://doi.org/10.1016/j.amjcard.2010.11.012

Pereira Sousa, J., Neves, H., & Pais-Vieira, M. (2021). Does symptom recognition improve self-care in patients with heart failure? A pilot study randomized controlled trial. Nursing Reports, 11(2), 418–429. https://doi.org/10.3390/nursrep11020040

Piña, I. L., Allen, L. A., & Desai, N. R. (2021). Managing the economic challenges in the treatment of heart failure. BMC Cardiovascular Disorders, 21(1), 612. https://doi.org/10.1186/s12872-021-02408-5

Quanbeck, A. (2019). Using stakeholder values to promote the implementation of an evidence-based mobile health intervention for addiction treatment in primary care settings. JMIR mHealth and uHealth, 7(6), e13301. https://doi.org/10.2196/13301

Rahmani, A., Vahedian-Azimi, A., Sirati-Nir, M., Norouzadeh, R., Rozdar, H., & Sahebkar, A. (2020). The effect of the teach-back method on knowledge, performance, readmission, and quality of life in heart failure patients. Cardiology Research and Practice, 2020, 8897881. https://doi.org/10.1155/2020/8897881

Singh, R., Javed, Z., Yahya, T., Valero-Elizondo, J., Acquah, I., Hyder, A. A., Maqsood, M. H., Amin, Z., Al-Kindi, S., Cainzos-Achirica, M., & Nasir, K. (2021). Community and social context: An important social determinant of cardiovascular disease. Methodist DeBakey Cardiovascular Journal, 17(4), 15–27. https://doi.org/10.14797/mdcvj.846

Ten Ham-Baloyi, W. (2022). Assisting nurses with evidence-based practice: A case for the Knowledge-to-Action framework. Health SA Gesondheid, 27, 2118. https://doi.org/10.4102/hsag.v27i0.2118

Torres, C. P., Mendes, F. J., & Barbieri-Figueiredo, M. (2023). Use of “The Knowledge-to-Action Framework” for the implementation of evidence-based nursing in child and family care: Study protocol. PLOS ONE, 18(3), e0283656. https://doi.org/10.1371/journal.pone.0283656

World Health Organization. (2021). Cardiovascular diseases (CVDs). https://www.who.int/news-room/fact-sheets/detail/cardiovascular-diseases-(cvds)

Bashi, N., Karunanithi, M., Fatehi, F., Ding, H., & Walters, D. (2020). Remote monitoring of patients with heart failure: An overview of systematic reviews. Journal of Medical Internet Research, 22(1), e20017. https://doi.org/10.2196/20017

NR 716 Week 4 Translation Science and Synthesis

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